It follows a £14m investment from the UK government.
A south Wales factory is one of two in the UK that will be producing millions of face masks each week.
The UK Government has announced a 14 million pound investment to set up production lines at the British Rototherm Group in Port Talbot and Cookson & Clegg in Blackburn.
Another site in Livingston, Scotland, will start to produce face coverings in the coming weeks.
The production sites will ensure that public demand does not impact on the supply of higher-grade face masks for NHS front line staff.
From Friday, it'll be mandatory to wear a face covering in shops in England while in Wales it'll be compulsory to wear them on public transport from next Monday.
The Chancellor of the Duchy of Lancaster Michael Gove said: "This is a major step to ensure that this country can meet any increase in demand for face coverings by working with British firms to establish the capability, capacity and skills required to manufacture these items at scale.
"These production lines will be able to get millions of face coverings to the public, without putting any additional pressure on NHS supply chains.
"It is fantastic to see companies in Lancashire, Neath Port Talbot and West Lothian coming together to provide face coverings for every corner of our United Kingdom."
The UK Government has bought ten production lines, which include 34 tons of equipment and machinery, and following checks and testing at a machine manufacturer, DCR Machines in Leeds, the machines have been set up across the UK.
A further ten production lines have been commissioned from a UK automotive company, Expert Tooling and Automation Ltd, based in Coventry.
The manufacturers will produce millions of masks each week.
The first production lines are being established at:
The British Rototherm Group, in Port Talbot, Wales.
Cookson & Clegg, Blackburn
Transcal, in Livingston, Scotland
Secretary of State for Wales Simon Hart said: "As our economy bounces back from the coronavirus pandemic and people look to get back to work safely, it is vital that our supply of protective equipment meets demand.
"Firms like Rototherm in Port Talbot will ensure we have a strong domestic manufacturing capability and that high-quality face coverings are available to everyone who needs them."