The two cases are not linked but both had recently returned from Italy.
The Chief Medical Officer for Wales, Dr Frank Atherton, has confirmed that two further patients in Wales have tested positive for Coronavirus (COVID -19).
The first patient is resident in the Neath Port Talbot local authority area, and has recently returned from Southern Italy.
The second patient is resident in the Newport local authority area, and has recently returned from Northern Italy.
Both patients are being managed in clinically appropriate settings.
It takes the total number of Coronavirus cases in Wales to 6.
Yesterday, it was confirmed two people from Pembrokeshire who had also returned from Italy had tested positive for the virus.
That follows two earlier cases in Swansea and Cardiff.
Dr Atherton said: "I can confirm that two additional individuals in Wales have tested positive for coronavirus (COVID-19), bringing the total number of positive cases in Wales to six.
"Both individuals are being managed in clinically appropriate settings. All appropriate measures to provide care for the individuals and to reduce the risk of transmission to others are being taken.
"I’d like to take this opportunity to assure the public that Wales and the whole of the UK is prepared for these types of incidents. Working with our partners in Wales and the UK, we have implemented our planned response, with robust infection control measures in place to protect the health of the public."
Dr Giri Shankar, Incident Director for the Novel Coronavirus (COVID-19) outbreak response at Public Health Wales, said:
"The Chief Medical Officer for Wales has this morning (9 March) announced two further Novel Coronavirus (COVID-19) cases in Wales, bringing the total number of confirmed cases in Wales to six.
"The process of identifying and contacting close contacts of the two new cases is underway, and we are taking all appropriate actions to protect the public’s health.
"We can confirm that the two individuals are not linked to one another, and that they both travelled separately back to Wales from different parts of Italy.
"The individuals are being managed in clinically appropriate settings based on the assessment of a specialist infectious disease consultant.
“The public can be assured that Wales and the whole of the UK is prepared for these types of incidents. Working with our partners in Wales and the UK, we have implemented our planned response, with robust infection control measures in place to protect the health of the public.
"All Welsh residents who meet the current testing criteria for Novel Coronavirus (COVID-19) are being offered testing. As of Friday 6 March, 634 people in Wales have been tested for Novel Coronavirus (COVID-19). We will now be publishing the number of people tested in Wales every Thursday at 3pm.
"We would encourage people to check the updated advice for returning travellers, which now includes guidance for those returning from Italy, China, Thailand, Japan, South Korea, Hong Kong, Taiwan, Singapore, Malaysia, Macau, Vietnam, Cambodia, Laos, Myanmar, and Iran.
"Members of the public can help protect themselves and others by always carrying tissues, and using them to catch coughs or sneezes. They should bin the tissue, and to kill the germs, wash their hands with soap and water, or use a sanitiser gel. This is the best way to slow the spread of most germs, including Novel Coronavirus (COVID-19).
"Public Health Wales’ trained scientists are now conducting the Novel Coronavirus (COVID-19) diagnostic test in Wales. Over 90 per cent of the individuals who have been tested in Wales have been offered testing in their own home, making it as convenient as possible for them, as well as protecting our ambulance and hospital resources for those who need it most. We are not able to comment on individual cases for reasons of patient confidentiality."
Coronavirus presents with flu-like symptoms including a fever, a cough, or difficulty breathing. The current evidence is that most cases appear to be mild.
The number of confirmed cases of Novel Coronavirus (COVID-19) in the UK, and the number of tests undertaken in the UK, are available from Department of Health and Social Care and Public Health England (PHE).
It's as measure are being taken to protect frontline staff in Wales.
GP surgeries across Wales will receive packs of face masks, gloves and aprons for their personal protection as they treat people with suspected Coronavirus, Health Minister Vaughan Gething announced today.
Packs were prepared over the weekend, and will be distributed to the 640 GP surgeries in Wales this week.
The Minister also authorised Personal Protection Equipment to be released from stockpiles for use by front line NHS and social services staff.
Health Minister Vaughan Gething said:
“These packs are part of robust infection control measures that we have in place, and I want to reassure people that we are working closely with NHS Wales and social services across the country to implement our planned response.
“It is important that frontline medical and social care staff have the equipment they need to keep them safe while they help people with suspected Coronavirus.
“The face masks, gloves and aprons are part of a stockpile that we have in place as part of our contingency planning should they be needed to support our NHS and social services.